Week 16 kicks off with one of the biggest games of the 2025 regular season, and one chock full of playoff ramifications when the Los Angeles Rams visit the Seattle Seahawks on Thursday night.
The NFC West rivals enter with identical 11-3 records atop the conference. The Seahawks have won four consecutive games since a Week 11 loss at the Rams. That victory has Los Angeles atop the NFC standings, with Seattle currently in the top wild-card spot.
A win on Thursday night very well could propel the Rams to the division title and home-field advantage in the NFC. A loss, and Los Angeles risks going on the road throughout its playoff run. And whichever team loses risks falling into a tie with 10-4 San Francisco, which plays at Indianapolis on Monday night.
ODDS AND TRENDS
The Seahawks are a consensus 1.5-point favorite at home. The line has held steady this week at BetMGM, where the Rams have been backed by 64% of the total spread-line bets and 59% of the money.
Los Angeles’ moneyline has also been popular, drawing 67% and 57% of the action, respectively, while shifting from -115 to +105.
The total points line of 42 is down significantly from opening at 45.5, due in large part to the unknown status of Rams wide receiver Davante Adams. The Over has been backed by 61% of the money.
PLAYER PROPS
–Rams TE Terrance Ferguson Over 19.5 Receiving Yards (-115 at BetMGM): Ferguson figures to be one of the beneficiaries of Adams being doubtful to play due to a hamstring injury. This has been the most popular Rams-based player prop at the book, even though the rookie has only one catch for 6 yards over his past five games. Ferguson has six catches for 144 yards and one touchdown on the season.
–Seahawks QB Sam Darnold 200+ Passing Yards (-223 at DraftKings): This has been the most popular player prop at the book with Darnold topping 200 passing yards in 11 of his past 13 games. He threw for 279 in the first matchup, but also was picked off four times. Seattle’s offense failed to score a touchdown last week and has struggled in the first half much of the season. If you’re looking for a bigger potential pay out, Darnold is -125 to throw for 220+ and +133 to throw for 240+ yards.
INSIDE EDGE
Seahawks offensive coordinator Klint Kubiak is known for his play-action passing game. However, Seattle ranks third-worst in the NFL with a success rate of just 39.3% on plays with motion this season, according to Inside Edge’s Remarkable engine.
KEY STATS
–Rams quarterback Matthew Stafford leads the NFL with a passer rating of 126.2 on passes to the right side of the field this season.
–Seattle’s defense ranks second in the league in opponents’ scoring, allowing just 17.3 points per game.
INJURY REPORT
Rams coach Sean McVay said he likely would wait until game time to make a decision on Adams, who aggravated the injury while running a deep route on Sunday in Los Angeles’ 41-34 victory against visiting Detroit.
“I’m not ruling anyone out,” McVay said Tuesday. “He just got his hamstring. He felt it a little bit, and it’s something he’s been dealing with, and he’s as tough as it gets. Want to be able to see what it looks like with the time we have.”
Adams has twice previously dealt with hamstring issues this season, his first with the Rams. He has 60 catches for 789 yards.
Rams defensive end Braden Fiske (ankle) is listed as questionable.
Stafford is a leading MVP contender with a league-leading 37 touchdown passes and 3,722 yards through the air, second only to the 3,931 of the Dallas Cowboys’ Dak Prescott.
Seahawks left tackle Charles Cross, who sustained a hamstring injury on Jason Myers’ game-winning kick Sunday, was ruled out of the contest on Wednesday.
“We’re just trying to gather the info right now, exhausting all options to see how fast we can get him back,” Seahawks coach Mike Macdonald said of Cross.
FLUTTERING HAWKS
While the Seahawks’ Jaxon Smith-Njigba leads the NFL with 1,541 receiving yards, the rest of the offense has stalled. Seattle’s offense has scored just six first-half points in each of its past three games (not counting an interception return for a TD).
The Seahawks likely will need more than that against a Rams team that has scored 40-plus points in each of its past two contests.
“We just need to get together and understand the game plan and execute at the end of the day,” Smith-Njigba said. “And I’ll leave it at that.”
Seattle managed a season-low 50 rushing yards against the Colts, with Kenneth Walker III totaling just 17 yards on nine attempts.
“We didn’t run it the way we wanted to,” Macdonald said. “It’s kind of a little bit of everything right now. A little bit late in the year to be saying that. So, I mean, we got to pick it up, really, on all fronts.”
“What a crazy week to be playing on a Thursday,” McVay said. “This is a good challenge. … It’s a blessing to be able to play in meaningful games this late in the season.” –McVay, who admitted he hasn’t gotten much sleep this week after his wife Veronika gave birth to son Christian Alexander McVay on Monday morning.
PREDICTION
Seattle’s offensive line already was struggling before losing Darnold’s stalwart blind-side protector for this game. Minus Cross, the Seahawks will continue to struggle running the ball and Darnold will be prone to the types of poor decisions under duress that put Seattle in a 14-3 hole in the first meeting. –Rams 23, Seahawks 20
